Metallkomplexe mit biologisch wichtigen Liganden, XLI [1]. Platin(II)- und Cobalt(III)-Komplexe von Monosaccharid-Derivaten mit Metall-Schwefel- und Metall-Kohlenstoff-Bindungen / Metal Complexes with Biologically Important Ligands, XLI [1]. Platinum(II) and Cobalt(III) Complexes of Monosaccharide Derivatives with Metal-Sulfur and Metal-Carbon Bonds

Abstract

The reaction of bis(2,3,4,6-tetra-0-acetyl-β-D-glucopyranosyl)disulfide with (Ph3P)2Pt(C2H4) gives cis-di(2,3,4,6-tetra-0-acetyl-l-mercapto-β-D-glucopyranosid)bis(triphenylphosphane)platinum (II). A dithiocarbimato complex (Ph3P)2Pt(S2CNR) has been isolated from cis-(Ph3P)2PtCl2, CS2 and 1-0-Methyl-2-amino-2-deoxy-4,6-benzyliden-α,β-D-glucopyranoside. Metal complexes with metal-carbon bonds have been prepared by oxidative addition of monosaccharide halides to (Ph3P)2Pt(C2H4) or to cobalt(I) cobaloxime, respectively. From the reaction of (Ph3P)2Pt(C2H4) with 2,3,4,6 -Tetra-O-acetyl-α-D-glucopyranosyl-bromide the anomers trans-(α- and β-glucopyranosyl) Pt(PPh3)2Br have been obtained. This indicates a radical reaction.