Synthesis and antimicrobial evaluation of isoxazole-substituted 1,3,4-oxadiazoles

Author:

Marri Srinivas,Kakkerla Ramu,Murali Krishna Mudumba Phali Surya,Venkat Rajam Manchikatla

Abstract

Abstract Synthesis of N-(5-methylisoxazol-3-yl)-2-(5-aryl-1,3,4-oxadiazol-2-yl)acetamides 5a–k was achieved from readily available materials. The compounds were screened for their in vitro antimicrobial activity against representative bacterial and fungal strains. Compounds 5b, 5d and 5f exhibit good activity.

Publisher

Walter de Gruyter GmbH

Subject

Organic Chemistry

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