Elastin biology and tissue engineering with adult cells-Reference-Cited by-同舟云学术

Elastin biology and tissue engineering with adult cells

Published:2013-04-01 Issue:2 Volume:4 Page:173-185
ISSN:1868-503X
Container-title:BioMolecular Concepts
language:
Short-container-title:

Author:

Saitow Cassandra B.¹,Wise Steven G.,Weiss Anthony S.²,Castellot John J.³,Kaplan David L.¹

Affiliation:

1. 1Tufts University, Department of Biomedical Engineering, Medford, MA, 02155, USA

2. 3Molecular Biosciences, University of Sydney, Sydney, New South Wales, Australia

3. 4Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA, 02111, USA

Abstract

AbstractThe inability of adult cells to produce well-organized, robust elastic fibers has long been a barrier to the successful engineering of certain tissues. In this review, we focus primarily on elastin with respect to tissue-engineered vascular substitutes. To understand elastin regulation during normal development, we describe the role of various elastic fiber accessory proteins. Biochemical pathways regulating expression of the elastin gene are addressed, with particular focus on tissue-engineering research using adult-derived cells.

Publisher

Walter de Gruyter GmbH

Subject

Cellular and Molecular Neuroscience,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://www.degruyter.com/downloadpdf/journals/bmc/4/2/article-p173.xml

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