A New Chlorine-containing Sesquiterpene Lactone from Achillea ligustica

Author:

Hegazya Mohamed-Elamir F.1,Mohamed Abou El-Hamd H.2,El-Sayed Magdi A.3,Ohta Shinji4

Affiliation:

1. Chemistry of Medicinal Plant Department, National Research Center, Dokki, Cairo, Egypt

2. Department of Chemistry, Aswan-Faculty of Science, South Valley University, Aswan, Egypt

3. Department of Botany, Aswan-Faculty of Science, South Valley University, Aswan, Egypt

4. Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga 526-0829, Japan

Abstract

Chromatographic investigation of the methylene chloride/methanol extract of the aerial parts of Achillea ligustica afforded a new chlorine-containing sesquiterpene lactone as well as two known compounds. The structures of the compounds were determined by comprehensive NMR studies, including DEPT, COSY, NOE, HMQC, HMBC and HRMS. The neurotrophic activity of the new compound has been measured.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

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