Diterpenes from Sideritis infernalis and S. candicans

Author:

Fraga Braulio M.1,Bressa Carlo1,Fernández Concepción1,González Pedro2,Guillermo Ricardo2,Hernández Melchor G.1

Affiliation:

1. Instituto de Productos Naturales y Agrobiología, CSIC,Avda. Astrofísico F. Sánchez 3, 38206-La Laguna, Tenerife, Canary Islands, Spain

2. Instituto de Bioorgánica “Antonio González”, Universidad de La Laguna, Tenerife, Spain

Abstract

A phytochemical study of Sideritis infernalis led to the isolation of the new nor-diterpene adejone (17-nor-7α,18-dihydroxy-ent-kaur-16-one). The biosynthesis of this compound implies the decarboxylation of an epoxy-acid as the last step. In addition, three diterpenes with an ent-kaurene skeleton, episideridiol, candicandiol 7α-monoacetate and candidiol 15α-monoacetate, have been isolated from S. candicans for the first time in nature.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

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