Author:
Miller Bradley S.,Spratt Eve G.,Himes John H.,Condon Doreen,Summer Andrea,Papa Carrie E.,Brady Kathleen T.
Abstract
AbstractThe long-lasting impact of different neglectful environments on growth in children is not well studied. Three groups of children, 3–10 years old, were recruited (n=60): previously institutionalized international adoptees living in stable home environments for at least 2 years (IA; n=15), children with a history of neglect born in the USA (USN; n=17), and controls (n=28). Children underwent physical examination, anthropometry, and collection of serum for growth parameters. Mean height standard deviation scores (SDS) were different (p<0.05). Age-adjusted head circumference (HC) was significantly smaller (p<0.05) in IAs. Insulin growth factor (IGF-1), a marker of growth hormone action, was higher in US neglected children. IGF-1 adjusted for age and weight SDS were different (p<0.05) between control and US neglect groups. The degree of growth failure in height and HC in IAs was more severe than neglected US children. These findings may reflect differences between the impact of chronic and intermittent deprivation on the growth hormone system.
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Pediatrics, Perinatology, and Child Health
Reference36 articles.
1. The health of children adopted from;Johnson;Romania Am Med Assoc,1992
2. MO Insulin - like growth factors nutrition and growth;Savage;World Rev Nutr Diet,2013
3. Medical diagnoses and growth of children residing in Russian orphanages;Miller;Acta Paediatr,2007
4. of children adopted from China;Miller;Health Pediatrics,2000
5. Self - regulation in newly arrived international adoptees;Tirella;Phys Ther,2011
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