Synapses, networks, brain development – funding basic neuroscience research in Germany by the Schram Foundation

Author:

Schulte Dorothea1,Rosenmund Christian2ORCID,Gundelfinger Eckart D.3

Affiliation:

1. Neurologisches Institut (Edinger Institut), Universitätsklinikum Frankfurt , Frankfurt , Germany

2. Institut für Neurophysiologie , Charite Universitätsmedizin Berlin , 10117 Berlin , Germany

3. Abteilung Neurochemie und Molekularbiologie, Leibniz-Institut für Neurobiologie , 39118 Magdeburg , Germany

Abstract

Abstract Research driven solely by curiosity and the desire to understand fundamental principles of brain function. The freedom to address important questions with bold, sometimes risky experiments. A platform for open scientific exchange and discussions at highest academic level to provide new impulses to the field. And a growing number of scientists who share the passion for neuroscience and who join forces to tackle some of the big mysteries that surround the brain. These visions together with the deep conviction that basic research is the fundament needed for any progress in applied science motivated Dr. Armin Schram to create the foundation that carries his name. They are also the ideals that the foundation still pursues, and to date, 26 research proposals designed by individual researchers or small teams have been, or are, supported in this spirit. Here, we introduce the reader to the individual scientists who were awarded grants by the Schram Foundation over the years, highlight some of the many discoveries made in the course of their studies and list some of the key publications that arose from this work.

Publisher

Walter de Gruyter GmbH

Subject

Neurology (clinical),Neurology

Reference41 articles.

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3. Dieterich, D.C., Karpova, A., Mikhaylova, M., Zdobnova, I., König, I., Landwehr, M., Kreutz, M., Smalla, K.-H., Richter, K., Landgraf, P., et al. (2008). Caldendrin-Jacob: A protein liaison that couples NMDA receptor signalling to the nucleus. PLoS Biol. 6, e34, https://doi.org/10.1371/journal.pbio.0060034.

4. Elgueta, C. and Bartos, M. (2019). Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells. Nat. Commun. 10, 5561, https://doi.org/10.1038/s41467-019-13533-3.

5. Engelhardt, M., Hamad, M.I.K., Jack, A., Ahmed, K., König, J., Rennau, L.M., Jamann, N., Räk, A., Schönfelder, S., Riedel, C., et al. (2018). Interneuron synaptopathy in developing rat cortex induced by the pro-inflammatory cytokine LIF. Exp. Neurol. 302, 169–180, https://doi.org/10.1016/j.expneurol.2017.12.011.

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