Properties of Powder Composite Polyhydroxybutyrate–Chitosan-Calcium Phosphate System
Author:
Medvecky L.1, Stulajterova R.1, Giretova M.1, Faberova M.1
Affiliation:
1. Institute of Materials Research of Slovak Academy of Sciences , Kosice , Slovakia
Abstract
Abstract
Prepared powder polyhydroxybutyrate – chitosan - calcium phosphate composite system with 10 wt % of biopolymer component can be utilized as biocement which is characterized by the prolonged setting time and achieves wash out resistance after 5 minutes of setting. The origin powder tetracalcium phosphate/nanomonetite agglomerates were coated with the thin layer of biopolymer which decelerates both the transformation rate of calcium phosphates and hardening process of composites. The porosity of hardened composite was around 62% and the compressive strength (8 MPa) was close to trabecular bone. No cytotoxicity of composite resulted from live/dead staining of osteoblasts cultured on substrates.
Publisher
Walter de Gruyter GmbH
Subject
Metals and Alloys,Mechanics of Materials
Reference32 articles.
1. [1] Agrawal, CM., Athanasiou, KA.: J. Biomed. Mater. Res. Part A, vol. 38, 1997, p. 105-114 2. [2] Linhart, W., Peters, F., Lehmann, W., Schwarz, K., Schilling, AF., Amling, M., Rueger, J. M., Epple, M.: J. Biomed. Mater. Res. Part A, vol.54, 2001, p. 162–17110.1002/1097-4636(200102)54:2<162::AID-JBM2>3.0.CO;2-3 3. [3] Schiller, C., Epple, M.: Biomaterials, vol. 24, 2003, p. 2037–204310.1016/S0142-9612(02)00634-8 4. [4] Schiller, C., Rasche, C., Wehmöller, M., Beckmann, F., Eufinger, H., Epple, M., Weihe, S.: Biomaterials, vol. 25, 2004, p. 1239–124710.1016/j.biomaterials.2003.08.047 5. [5] Verheyen, CCP. M., deWijn, JR., Van Blitterswijk, CA., De Groot, K.: J. Biomed. Mater. Res. Part A, vol.26, 1992, p. 1277–129610.1002/jbm.820261003
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