Notizen: Synthesis and Electron Spin Resonance Study of Spin-Labelled Compounds Related to Tumour- Growth Inhibitory Nitroarylaziridines-Reference-Cited by-同舟云学术

Notizen: Synthesis and Electron Spin Resonance Study of Spin-Labelled Compounds Related to Tumour- Growth Inhibitory Nitroarylaziridines

Published:1976-06-01 Issue:5-6 Volume:31 Page:328-330
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Dodd N.¹,Harcus R.²,Preston P.³

Affiliation:

1. Christie Hospital and Holt Radium Institute, Manchester

2. Department of Chemistry, Heriot-Watt University, Riccarton, Currie, Edinbugh

3. Department of Chemistry, Heriot-Watt University, Riccarton, Currie, Edinburgh

Abstract

Abstract Three stable free radicals have been prepared which are akin to 5-aziridino-2,4-dinitrobenzamide (CB 1954) ; these compounds all contain a nitroxide function. The metabolism and excretion of two such compounds in mice has been monitored by electron spin resonance (ESR) spectroscopy and compared with that of the simpler nitioxide, 4-keto-2,2,6,6-tetramethylpiperidino-1-oxyl (tempone).

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-1976-5-621/pdf

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metabolism of the stable nitroxyl radical 4-oxo-2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPONE);European Journal of Pharmaceutical Sciences;1999-04

2. Nitroxide metabolism in the human keratinocyte cell line HaCaT11Dedicated to Prof. Dr. G. Heinisch, Innsbruck, Austria, on the occasion of his 60th birthday.;Free Radical Biology and Medicine;1999-04

3. A Critical Appraisal of the Evolution of N-Nitrosoureas as Anticancer Drugs;Chemical Reviews;1997-05-01

4. Nitroxyl Radicals for Cancer Chemotherapy;Bioactive Spin Labels;1992

5. In vivo analysis of nitroxide radicals injected into small animals by L-band ESR technique;Physics in Medicine and Biology;1989-09-01