New compounds from Sarcophyton glaucom-derived Penicillium sp.-Reference-Cited by-同舟云学术

New compounds from Sarcophyton glaucom-derived Penicillium sp.

Published:2021-12-15 Issue:0 Volume:0 Page:
ISSN:0939-5075
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Shaaban Mohamed¹²^ORCID

Affiliation:

1. Chemistry of Natural Compounds Department , Division of Pharmaceutical Industries, National Research Centre , El-Behoos St. 33 , Dokki , Cairo 12622 , Egypt

2. University of Göttingen, Institute of Organic and Biomolecular Chemistry , Tammannstrasse 2, D-37077 , Göttingen , Germany

Abstract

Abstract Further investigation of the residual bioactive compounds produced by the soft coral Sarcophyton glaucom-derived Penicillium sp. MMA afforded five new compounds assigned as 9-methoxy-penicyrone A (1), 9-methoxy-penicyrone B (2), 3-hydroxy-2,2,4-trimethyl-pentyl ester (3), 3-hydroxy-1-isopropyl-2,2-dimethyl-propyl ester (4), and 3-isobutyryloxy-2,2,4-trimethyl-pentyl linoleate (5). Additional six known compounds were isolated: penicyrones A–B (6, 7), 4-(2-hydroxy-3-butynoxy)benzoic acid (8), cyclopenol (9), aspermytin A (10), and aurantiomide A (11). Structures of the new compounds (1–5) were identified by 1D (1H & 13C) and 2 D (1H–1H COSY, HMBC and NOESY) NMR and HRESI-MS spectroscopic data. Biologically, the antimicrobial activities of the obtained compounds were studied as well.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-2021-0236/pdf

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