Notizen: Photosensitized Effects of Furocoumarins: the Possible Role of Singlet Oxygen-Reference-Cited by-同舟云学术

Notizen: Photosensitized Effects of Furocoumarins: the Possible Role of Singlet Oxygen

Published:1983-10-01 Issue:9-10 Volume:38 Page:866-869
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Vedaldi Daniela¹,Dall'Acqua Francesco²,Gennaro Armando³,Rodighiero Giovanni²

Affiliation:

1. Institute of Pharmaceutical Chemistry , Via Marzolo, 5-35100 Padova, Italy

2. Institute of Pharmaceutical Chemistry, Via Marzolo, 5-35100 Padova, Italy

3. Institute of Physical Chemistry and Electrochemistry of the Padua University and Centro di Studio sulla Chimica del Farmaco e dei Prodotti Biologicamente Attivi del CNR , Via Marzolo, 5-35100 Padova, Italy

Abstract

Abstract The capacity of various furocoumarins to generate singlet oxygen in aqueous solution has been determined. The antiproliferative and the skin-photosensitizing activities of the same furocoumarins did not show any correlation with the capacity to generate the singlet oxygen, while these photobiological properties could be correlated with the capacity of furocoumarins to induce photolesions to the DNA.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-1983-9-1033/pdf

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