Fungitoxic Isoflavones from Lupinus albus and other Lupinus Species

Author:

Ingham John L.1,Tahara Satoshi2,Harborne Jeffrey B.2

Affiliation:

1. Phytochemical Unit, Departm ent of Botany, University of Reading, Reading RG6 2AS, England

2. Departm ent of Agricultural Chemistry, Faculty of Agriculture, Hokkaido University, Sapporo 060, Japan

Abstract

The constitutive isoflavones genistein, 2'-hydroxygenistein, wighteone and luteone have been isolated in varying amounts from methanolic leaf washings of eight species belonging to the legume genus Lupinus. These four compounds likewise occur in the flower buds, stems, roots and immature pods of L. albus, and in stems and roots of L. angustifolius and L. mutabilis. A minor isoflavone present in L. albus and L. luteus leaf washings has been identified by chemical and spectroscopic procedures as 5,7,4'-trihydroxy-3-methoxy-6-(3,3-dimethylallyl)isoflavone (lupisoflavone). Apart from genistein, 2'-hydroxygenistein, wighteone and luteone, the roots of L. albus also contain alpinumisoflavone, licoisoflavone B and 6,3'-di-(3,3-dimethylallyl)genistein (lupalbigenin)

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

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