Acquired factor VIII deficiency in a nulliparous patient undergoing induction of labor-Reference-Cited by-同舟云学术

Acquired factor VIII deficiency in a nulliparous patient undergoing induction of labor

Published:2024-01-01 Issue:1 Volume:13 Page:
ISSN:2192-8959
Container-title:Case Reports in Perinatal Medicine
language:en
Short-container-title:

Author:

Zayat Nawras¹²^ORCID,Huang Shirley²,Filipovic Anthony²,Bartley Lorie³,Akkary Wissam³

Affiliation:

1. 205134 Montefiore Medical Center, Jack D Weiler Hospital , Bronx, NY , USA

2. 12298 State University of New York, Downstate Health Sciences University , Brooklyn , NY , USA

3. 24513 Kings County Hospital Center , Brooklyn , NY , USA

Abstract

Abstract Objectives To present a case of acquired factor VIII deficiency in the setting of labor and describe the challenges of its diagnosis and treatment. Case presentation A 31-year-old woman was diagnosed with acquired factor VIII deficiency while undergoing induction of labor. Her labor and post operative course were complicated by epidural hematoma formation, prolonged postoperative surgical site bleeding, and subcutaneous hematoma. Management included blood products, human Factor VII, rituximab, and a steroid taper. Conclusions Acquired factor VIII deficiency can be challenging to diagnose and should be considered in the differential diagnosis in patients with prolonged bleeding accompanied by a prolonged activated partial thromboplastin time (aPTT).

Publisher

Walter de Gruyter GmbH

Link

https://www.degruyter.com/document/doi/10.1515/crpm-2023-0004/pdf

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