Haemophagocytic lymphohistiocytosis during pregnancy: a case presentation and literature review
Author:
Fávero Vanraes Larissa1ORCID, Beckers Veerle2, Van Berkel Kim3, Gucciardo Leonardo4, Faron Gilles4
Affiliation:
1. Department of Gynaecology and Obstetrics , Vrije Universiteit Brussel, Brussels Health Campus , Brussels , Belgium 2. Division of Haematology, Department of Internal Medicine , Vrije Universiteit Brussel, Brussels Health Campus , Brussels , Belgium 3. Department of Medical Genetics , Vrije Universiteit Brussel, Brussels Health Campus , Brussels , Belgium 4. Division of Prenatal Medicine and Obstetrics, Department of Gynaecology and Obstetrics , Vrije Universiteit Brussel, Brussels Health Campus , Brussels , Belgium
Abstract
Abstract
Objectives
Haemophagocytic lymphohistiocytosis (HLH) is a potentially fatal disorder of the immune system that typically occurs in the paediatric population. Diagnosing this rare disease in the adult population is challenging, particularly during pregnancy.
Case presentation
We present a case of a gravid patient developing HLH at week 13 of gestation undergoing a medical termination of pregnancy at 27 weeks due to anhydramnios and associated stopped foetal growth.
Conclusions
Disease triggers could vary from a simple viral infection to the pregnancy as such causing the disorder. Treatment should benefit the mother and limit the foetal harm.
Publisher
Walter de Gruyter GmbH
Subject
Obstetrics and Gynecology,Embryology,Pediatrics, Perinatology and Child Health
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