Fabrication and characterization of three-dimensional polycaprolactone/sodium alginate and egg whites and eggshells hybrid scaffold in bone tissue engineering-Reference-Cited by-同舟云学术

Fabrication and characterization of three-dimensional polycaprolactone/sodium alginate and egg whites and eggshells hybrid scaffold in bone tissue engineering

Published:2022-11-11 Issue:1 Volume:43 Page:47-52
ISSN:0334-6447
Container-title:Journal of Polymer Engineering
language:en
Short-container-title:

Author:

Rezaei Hessam¹²^ORCID,Shahrezaee Mostafa¹,Monfared Marziyeh Jalali³,Nikjou Mona²,Shahrezaee Mohammad Hossein¹⁴,Mohseni Mojdeh⁵⁶

Affiliation:

1. Department of Orthopedic Surgery , School of Medicine, Aja University of Medical Sciences , Tehran 1411718541 , Iran

2. Department of Biomedical Engineering, Science and Research Branch , Islamic Azad University , Tehran , Iran

3. Department of Biomaterials and Medicinal Chemistry Research Center , Aja University of Medical Sciences , Tehran , Iran

4. School of Dentistry , Tehran University of Medical Sciences , Tehran , Iran

5. Stem Cell and Regenerative Medicine Research Center , Iran University of Medical Sciences , Tehran , Iran

6. Eye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital , Iran University of Medical Sciences , Tehran , Iran

Abstract

Abstract The aim of this study was to fabricate three-dimensional bone scaffolds using polycaprolactone and egg shell powder. The scaffolds were coated with sodium alginate/egg white. SEM was used to investigate egg shell particles on the surface of each string of scaffolds. The presence of calcium carbonate in the scaffold structure was confirmed by microstructural analyses employing XRD. Egg shell-related functional groups were discovered using FTIR investigations. Bone cells were used to conduct biocompatibility tests on scaffolds (MG-63). Finally, scaffolds with the highest proportion of egg whites and eggshells have the best cell survival rate. It may be concluded that the PCL/7% Esh/15% Ew scaffold is a good option for application in bone tissue engineering.

Publisher

Walter de Gruyter GmbH

Subject

Materials Chemistry,Polymers and Plastics,General Chemical Engineering

Link

https://www.degruyter.com/document/doi/10.1515/polyeng-2022-0138/pdf

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