Life sciences and mass spectrometry: some personal reflections

Author:

Peter-Katalinic Jasna12ORCID

Affiliation:

1. Institute for Medical Physics and Biophysics (IMPB), University of Münster , Robert-Koch-Str. 31, D-48149 Münster , Germany

2. Department of Biotechnology , University of Rijeka , Radmile Matejcic 2, 51000 Rijeka , Croatia

Abstract

Abstract Molecular analysis of biological systems by mass spectrometry was in focus of technological developments in the second half of the 20th century, in which the issues of chemical identification of high molecular diversity by biophysical instrumental methods appeared as a mission impossible. By developing dialogs between researchers dealing with life sciences and medicine on one side and technology developers on the other, new horizons toward deciphering, identifying and quantifying of complex systems became a reality. Contributions toward this goal can be today considered as pioneering efforts delivered by a number of researchers, including generations of motivated students and associates.

Publisher

Walter de Gruyter GmbH

Subject

Clinical Biochemistry,Molecular Biology,Biochemistry

Reference42 articles.

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2. Bartkowiak, K., Wieczorek, M., Buck, F., Harder, S., Moldenhauer, J., Effenberger, K.E., Pantel, K., Peter-Katalinic, J., and Brandt, B.H. (2009). Two-dimensional differential gel electrophoresis of a cell line derived from a breast cancer micrometastasis revealed a stem/progenitor cell protein profile. J. Proteome Res. 8: 2004–2014, https://doi.org/10.1021/pr8009758.

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4. Bindila, L., Steiner, K., Mormann, M., Schäffer, C., Messner, P., and Peter-Katalinic, J. (2007). Sequencing of O-glycopeptides derived from S-layer glycoproteins containing very large carbohydrate chains by Fourier transform ion cyclotrone resonance infrared multiphoton dissociation mass spectrometry. Anal. Chem. 79: 3271–3279, https://doi.org/10.1021/ac0617363.

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