Recent updates in nanotechnological advances for wound healing: A narrative review

Author:

Chopra Hitesh1,Mohanta Yugal Kishore23,Mahanta Saurov4,Mohanta Tapan Kumar5,Singh Inderbir1,Avula Satya Kumar5,Mallick Sarada Prasanna6,Rabaan Ali A.789,AlSaihati Hajir10,Alsayyah Ahmed11,Alissa Mohammed12,Alturaifi Hussain R.13,AlAlwan Bader14,Attia Mohamed S.15,Chakraborty Sandip16,Dhama Kuldeep17

Affiliation:

1. Department of Pharmaceutics, Chitkara College of Pharmacy, Chitkara University , Rajpura , Punjab 140401 , India

2. Nano-Biotechnology and Translational Knowledge Laboratory, Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Techno City, 9th Mile , Ri-Bhoi , Baridua 793101, Meghalaya , India

3. Centre for Herbal Pharmacology and Environmental Sustainability, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education , Kelambakkam 603103, Tamil Nadu , India

4. Bioinformatics Division, National Institute of Electronics and Information Technology (NIELIT), Guwahati Centre , Guwahati , India

5. Biotech and Omics Lab, Natural and Medical Sciences Research Centre, University of Nizwa , Nizwa , 616 , Oman

6. Department of Biotechnology, Koneru Lakshmaiah Education Foundation , Vaddeswaram 522302, Andhra Pradesh , India

7. Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare , Dhahran 31311 , Saudi Arabia

8. College of Medicine, Alfaisal University , Riyadh 11533 , Saudi Arabia

9. Department of Public Health and Nutrition, The University of Haripur , Haripur 22610 , Pakistan

10. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hafr Al Batin , Hafr Al Batin 39831 , Saudi Arabia

11. Department of Pathology, College of Medicine, Imam Abdulrahman bin Faisal University , Dammam 31441 , Saudi Arabia

12. Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University , Al-Kharj 11942 , Saudi Arabia

13. Department of Laboratory and Blood Bank, King Fahad Hospital , Al Hofuf 36441 , Saudi Arabia

14. Clinical Laboratory Science Department, Mohammed Al-Mana College for Medical Sciences , Dammam 34222 , Saudi Arabia

15. Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University , Zagazig , Egypt

16. Department of Veterinary Microbiology, College of Veterinary Sciences and Animal Husbandry, R.K. Nagar , West Tripura , Tripura 799008 , India

17. Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar , Bareilly , Uttar Pradesh , India

Abstract

Abstract The repair and remodeling of injured tissues, known as wound healing, is a multifaceted process. The use of nanotechnology to speed up the healing process of wounds by promoting the right kind of mobility through different mechanisms has shown a lot of promise. Several nanotechnologies with novel properties have emerged in recent years, each of which targets a different issue associated with wound-healing processes. Through their antibacterial, anti-inflammatory, and angiogenic actions, nanomaterials may alter the wound microenvironment from a non-healing to a healing state. Wound dressings including hydrogels, gelatin sponges, films, and bandages may all benefit from the use of nanoparticles (NPs) to keep harmful microbes out. The addition of bioactive substances like antibiotics, NPs, and growth factors to certain dressings may further boost their efficacy. In conclusion, this review sheds light on wound healing that may be aided by the special features of materials based on nanotechnology. Although nanomaterials for wound healing show great promise, further study is needed before this promising area can convert its findings into consumer-friendly solutions.

Publisher

Walter de Gruyter GmbH

Subject

Surfaces, Coatings and Films,Process Chemistry and Technology,Energy Engineering and Power Technology,Biomaterials,Medicine (miscellaneous),Biotechnology

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