Recent investigations of bioactive natural products from endophytic, marine-derived, insect pathogenic fungi and Thai medicinal plants

Author:

Mahidol Chulabhorn1,Kittakoop Prasat1,Prachyawarakorn Vilailak1,Pailee Phanruethai1,Prawat Hunsa1,Ruchirawat Somsak1

Affiliation:

1. 1Chulabhorn Research Institute, Chulabhorn Graduate Institute, and Center of Excellence on Environmental Health and Toxicology (EHT), Kamphang Phet 6 Road, Laksi, Bangkok 10210, Thailand

Abstract

AbstractLiving organisms in Thailand are very diverse due to the unique geographical location of Thailand. The diversity of Thai bioresources has proven to be a rich source of biologically active compounds. The present review covers bioactive substances from Thai endophytic, marine-derived, insect pathogenic fungi and medicinal plants. Many new compounds isolated from Thai bioresources have diverse skeletons belonging to various classes of natural products. These compounds exhibited an array of biological activities, and some are of pharmaceutical interest. Bioactive compounds from Thai bioresources have not only attracted organic chemists to develop strategies for total synthesis, but also attracted (chemical) biologists to investigate the mechanisms of action. The chemistry and biology of some selected compounds are also discussed in this review.

Publisher

Walter de Gruyter GmbH

Subject

General Chemical Engineering,General Chemistry

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