Synthesis of biopolymer-polypeptide conjugates and their potential therapeutic interests-Reference-Cited by-同舟云学术

Synthesis of biopolymer-polypeptide conjugates and their potential therapeutic interests

Published:2023-10-17 Issue:0 Volume:0 Page:
ISSN:2365-6581
Container-title:Physical Sciences Reviews
language:en
Short-container-title:

Author:

Singh Amandeep¹^ORCID,Kumari Kamlesh²,Kundu Patit Paban¹³

Affiliation:

1. Department of Polymer Science and Technology , University of Calcutta , Kolkata , India

2. Department of Chemical Engineering , SLIET Longowal , Punjab , India

3. Department of Chemical Engineering , Indian Institute of Technology , Roorkee , India

Abstract

Abstract Biopolymer-based conjugates are widely used for numbers of biomedical applications. Materials scientists have become progressively interested in compounding biological-relevant entities with biopolymers into polymeric biohybrid framework. Biopolymer are conjugated with various fragments such as enzymes, proteins, nucleic acids as well as their analogues, peptidomimetics, peptides, fluorescent composites, avidin or streptavidin, biotin, polyethylene glycol, and various other bioactive compounds in order to serve a particular functionality in biomedical applications. In current chapter, a summary of various methods to synthesize biopolymer-peptide biohybrid conjugates and their prospective applications in biomedical field is presented.

Publisher

Walter de Gruyter GmbH

Subject

General Physics and Astronomy,General Materials Science,General Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/psr-2022-0185/pdf

Reference24 articles.

1. Sumerlin, BS. Proteins as initiators of controlled radical polymerization: grafting-from via ATRP and RAFT. ACS Macro Lett 2012;1:141–5. https://doi.org/10.1021/mz200176g.

2. Obermeyer, AC, Olsen, BD. Synthesis and application of protein-containing block copolymers. ACS Macro Lett 2015;4:101–10.

3. Hoffman, JM, Stayton, PS, Hoffman, AS, Lai, JJ. Stimuli-responsive reagent system for enabling microfluidic immunoassays with biomarker purification and enrichment. Bioconjugate Chem 2015;26:29–38. https://doi.org/10.1021/bc500522k.

4. DeChancie, J, Houk, KN. The origins of femtomolar protein−ligand binding: hydrogen-bond cooperativity and desolvation energetics in the biotin−(strept) avidin binding site. J Am Chem Soc 2007;129:5419–29. https://doi.org/10.1021/ja066950n.

5. Sylvestre, M, Lv, S, Yang, LF, Luera, N, Peeler, DJ, Chen, BM, et al.. Replacement of L-amino acid peptides with D-amino acid peptides mitigates anti-PEG antibody generation against polymer-peptide conjugates in mice. J Contr Release 2021;331:142–53. https://doi.org/10.1016/j.jconrel.2021.01.015.