Gender- and obesity-specific effect of apolipoprotein C3 gene (APOC3) –482C>T polymorphism on triglyceride concentration in Turkish adults

Abstract

AbstractApolipoprotein C3 (Randomly selected 1548 individuals (757 male and 791 female, mean age 49.9±11.8 years) were genotyped for –482C>T polymorphism using hybridization probes in a Real-Time PCR LC480 device.The –482TT genotype prevailed 9.9% in men and 11.5% in women. Association between 482C>T polymorphism and dyslipidemia (p=0.036, OR=1.42, 95%Cl=1.02–1.97) was found only in men. Analysis of variance showed that anthropometric and metabolic variables were not differently distributed in