Author:
Ducolomb R,Cadet J,Teoule R
Abstract
Abstract
The major product of uridine gamma irradiation in aerated aqueous solution (10-3 ᴍ, pH ~6) has been identified: N-(β-ᴅ-ribofuranosyl) -formamide. Thin-layer silica gel chromatography and spectroscopic methods (mass spectrometry. NMR, IR, optical rotation) enabled us to isolate and characterize this product.
It may be assumed that this substance resulted from the hydrolytic degradation of unstable hydroxy-hydroperoxides. It was also prepared by uridine oxydation with pertrifluoracetic acid.
A similar major compound in the radiolysis of uridylic acid has been found
Subject
General Biochemistry, Genetics and Molecular Biology
Cited by
6 articles.
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