The implementation of non-invasive prenatal testing (NIPT) in the Netherlands

Author:

Bilardo Caterina M.1ORCID

Affiliation:

1. Fetal Medicine Amsterdam UMC, location VUMC , Amsterdam , Netherlands

Abstract

Abstract In the Netherlands prenatal screening is offered as a mean to increase reproductive choices of couples. All women are counseled on the existing options by trained midwives. The government puts a great emphasis on informed choice and on womens’ opinions and reactions to screenings options. Since 2017 non-invasive prenatal testing (NIPT, cf-DNA) is offered as first tier screening for aneuploidies in the genome-wide (GW) variant at the cost of 175 Euro’s. Uptake is around 50%. This screenings offer is perceived as unconventional for the traditionally cautious Dutch system.

Publisher

Walter de Gruyter GmbH

Subject

Obstetrics and Gynaecology,Pediatrics, Perinatology, and Child Health

Reference28 articles.

1. Population Screening Act. Wet bevolkingsonderzoek. The Hague, 29 October 1992.

2. Health Council of the Netherlands (publication no. 2016/10). Wet op het bevolkingsonderzoek: NIPT als eerste test voor de syndromen van Down, Patau en Edwards. The Hague, The Netherlands; 2016.

3. Dondorp, W, de Wert, G, Bombard, Y, Bianchi, DW, Bergmann, C, Borry, P, et al.. Non‐invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening. Eur J Hum Genet 2015;23:1438–50. https://doi.org/10.1038/ejhg.2015.57.

4. Bunnik, EM, de Jong, A, Nijsingh, N, de Wert, GM. The new genetics and informed consent: differentiating choice to preserve autonomy. Bioethics 2013;27:348–55. https://doi.org/10.1111/bioe.12030.

5. RIVM. Rijks Instituut Volksgezondheid Milieu RIVM. Available from: https://www.pns.nl/prenatal-screening.

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