Chorioamnionitis has no impact on immunohistochemical expression of IL-6 in placental membranes of the late preterm delivery regardless of the membrane status-Reference-Cited by-同舟云学术

Chorioamnionitis has no impact on immunohistochemical expression of IL-6 in placental membranes of the late preterm delivery regardless of the membrane status

Published:2021-12-13 Issue:0 Volume:0 Page:
ISSN:0300-5577
Container-title:Journal of Perinatal Medicine
language:en
Short-container-title:

Author:

Benzon Zdeslav¹,Kuzmić Prusac Ivana²,Zekić Tomaš Sandra²,Vulić Marko¹,Vulić Luka³,Benzon Sandra¹,Stefanovic Vedran⁴^ORCID

Affiliation:

1. Department of Gynecology and Obstetrics , University Hospital and School of Medicine, University of Split , Split , Croatia

2. Institute for Pathology, University Hospital and School of Medicine , Split , Croatia

3. Department of Gynecology and Obstetrics , University Hospital Center “Sisters of Mercy” , Zagreb , Croatia

4. Department of Obstetrics and Gynecology , Fetomaternal Medical Center, Helsinki University Hospital and University of Helsinki , Helsinki , Finland

Abstract

Abstract Objectives To compare the immunohistochemical expression of IL-6 in placental membranes of late preterm delivery in women with histologically proven chorioamnionitis with and without preterm premature rupture of membranes (PPROM). Methods Fetal membranes were collected from 60 women who had late preterm delivery with histologic chorioamnionitis with and without PPROM (30 in each group). Immunohistochemistry for IL-6 was performed on formalin fixed and paraffin-embedded sections. The two groups were matched for age, body mass index and parity. SPSS Version 17.0 was used for statistical analysis. Results There was no difference in immunohistochemical expression of IL-6 in placental membranes of women with histologic chorioamnionitis regardless of the membrane status. Conclusions Chorioamnionitis has no impact on immunohistochemical expression of IL-6 in placental membranes of women with late preterm delivery despite the clinical presentation.

Publisher

Walter de Gruyter GmbH

Subject

Obstetrics and Gynecology,Pediatrics, Perinatology and Child Health

Link

https://www.degruyter.com/document/doi/10.1515/jpm-2021-0542/pdf

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