Three New Benzoic Acid Derivatives from the Glandular Excretion of Eriodictyon sessilifolium (Hydrophyllaceae)

Abstract

Eriodictyon sessilifolium, an endemic Hydrophyllaceae of Baja California (Mexico), has been studied for the natural products exuded by glandular trichomes covering its leaves and stems. Major components of this exudate were isolated and identified by spectroscopic methods to be 4-hydroxy-3-(2,3-dihydroxy-3-methylbutyl)-benzoic acid methyl ester (1), the natural methyl ester of anodendroic acid (2), and 2,2-dimethyl-3-hydroxychroman-6-carboxylic acid methyl ester (3). Possible biosynthetic relations between these new natural products are considered. In addition, 9 known flavonoid aglycones were identified as exudate constituents.