Author:
Cavaco Isa,Piedade Rita,Gil J. Pedro,Ribeiro Vera
Abstract
AbstractCytochrome P450 2C8 (CYP2C8) is a polymorphic phase I drug-metabolising enzyme involved in the metabolism of a wide variety of xenobiotics, as well as a proposed player in the regulation of vascular tone. Polymorphisms in this gene may have an impact on the metabolism of therapeutic drugs such as paclitaxel and verapamil. In this report we have determined the frequencies of the main non-synonymous
Subject
Biochemistry (medical),Clinical Biochemistry,General Medicine
Cited by
24 articles.
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