Helical self-assembly of an unusual pseudopeptide: crystallographic evidence-Reference-Cited by-同舟云学术

Helical self-assembly of an unusual pseudopeptide: crystallographic evidence

Published:2023-10-30 Issue:11-12 Volume:238 Page:373-378
ISSN:2194-4946
Container-title:Zeitschrift für Kristallographie - Crystalline Materials
language:en
Short-container-title:

Author:

Dutta Arpita¹,Das Suven²,Das Purak²

Affiliation:

1. Department of Chemistry , Rishi Bankim Chandra Evening College , Naihati , 24-Parganas (N), 743165 , India

2. Department of Chemistry , Rishi Bankim Chandra College for Women , Naihati , 24-Parganas (N), 743165 , India

Abstract

Abstract Pseudopeptides are a versatile class of organic building blocks having potential applications in a wide range of domains. In the current study, N and C termini protected l-alanine based short pseudopeptide was synthesized, where 5-aminoisophthalic acid (5-AIA), a rigid non-proteogenic γ-amino butyric acid was incorporated as C-terminal residue. The single crystal X-ray analysis revealed that the l-Ala residue of the aforesaid peptide adopts ϕ and ψ values characteristic of polyproline II conformation. Self-assembly of the pseudopeptide seems to represent a supramolecular helical architecture via NH⋯O, CH⋯O hydrogen bonding and π–π interactions.

Funder

SERB (DST), India

Publisher

Walter de Gruyter GmbH

Subject

Inorganic Chemistry,Condensed Matter Physics,General Materials Science

Link

https://www.degruyter.com/document/doi/10.1515/zkri-2023-0034/pdf

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