Affiliation:
1. School of Pharmacy, Jiangsu University, Zhenjiang Jiangsu 212013, China
2. Institute of Life Sciences Jiangsu University, Zhenjiang Jiangsu 212013, China
Abstract
Abstract
A virosome is an innovative hybrid drug delivery system with advantages of both viral and non-viral vectors. Studies have shown that a virosome can carry various biologically active molecules, such as nucleic acids, peptides, proteins and small organic molecules. Targeted drug delivery using virosome-based systems can be achieved through surface modifications of virosomes. A number of virosome- -based prophylactic and therapeutic products with high safety profiles are currently available in the market. Cancer treatment is a big battlefield for virosome-based drug delivery systems. This review provides an overview of the general concept, preparation procedures, working mechanisms, preclinical studies and clinical applications of virosomes in cancer treatment.
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Cited by
48 articles.
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