Affiliation:
1. Institut für Anorganische und Analytische Chemie der Technischen Universität, Postfach 3329. D-38023 Braunschweig
2. Fachbereich Chemie der Universität Oldenburg. Postfach 2503. D-26111 Oldenburg
Abstract
The base-catalyzed reaction of 2-oxo-2-hydro-1,3,5-trimethyl-1,3,5-triaza-2λ4-phosphorine- 4,6-dione (1) and of its trimethylsiloxy phosphorus(III) derivative (10) with various 3-thiazolines (2 -5 ) via five different pathways is described. In all cases, the corresponding 3-thiazoline adducts were formed. The different routes are compared with regard to reaction conditions and yields. In the reaction of 1 with 5,5-dimethyl-2-isopropyl-3-thiazoline (3) two diastereomers of 7 were formed, as established by 1H , 13C and 31P NMR spectroscopy. The structures of the products 6 and 8 were confirmed by X-ray analysis; the thiazolidine rings display a twist conformation through the sulfur atom. The molecules are linked via inversion centres by hydrogen bonds of the form N-H···O= C.
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5 articles.
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1. ETUDE DE L'ACTION DE L'OXYDE DU TRICHLOROPHOSPHINE SUR LES AMIDINESN-BENZIMIDAZOL-2-YL: SYNTHESE DES [1,2-a] BENZIMIDAZOLO-1,3,5,2-TRIAZAPHOSPHORINE-2-OXYDES;Phosphorus, Sulfur, and Silicon and the Related Elements;2014-02-05
2. ChemInform Abstract: Chemistry of the 1,3,5-Triaza-2-phosphorin-4,6-diones. Part 11. Base- Catalyzed Addition Reactions of 2-Oxo-2-hydro-1,3,5-trimethyl-1,3,5- triaza-2λ4-phosphorine-4,6-dione to the C=N Double Bond of 3- Thiazoline Heterocycles.;ChemInform;2010-08-04
3. NOUVELLE SYNTHÈSE DE [1,2-A]BENZIMIDAZOLO-1,3,5,2-TRIAZAPHOSPHORINES ET DE [1,2-A]BENZIMIDAZOLO-1,3,5,2- TRIAZAPHOSPHORINE-2-THIONES;Phosphorus, Sulfur, and Silicon and the Related Elements;2004-07-01
4. Six-membered Rings with Two or More Heteroatoms with at least One Phosphorus Atom;Phosphorus-Carbon Heterocyclic Chemistry;2001
5. The first synthesis of cyclic α‐amino phosphonic acid amides bearing the benzodiazaphosphorinanone system;Heteroatom Chemistry;1998-01