Clinical genetic testing and counselling in autism spectrum disorder-Reference-Cited by-同舟云学术

Clinical genetic testing and counselling in autism spectrum disorder

Published:2020-05-01 Issue:1 Volume:32 Page:31-37
ISSN:1863-5490
Container-title:Medizinische Genetik
language:en
Short-container-title:

Author:

Freitag Christine M.¹,Haslinger Denise¹,Yousaf Afsheen¹,Waltes Regina¹

Affiliation:

1. Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy , Autism Research and Intervention Center of Excellence , University Hospital Frankfurt, Goethe Universität , Deutschordenstr. 50 , Frankfurt am Main , Germany

Abstract

Abstract Autism spectrum disorders (ASDs) are phenotypically as well as genetically heterogeneous developmental disorders with a strong heritability. Clinical and basic science research has described many replicated genetic risk factors. Many findings can well be translated into clinical human genetic practice. The current article summarizes results of genetic studies in ASD, provides a diagnostic algorithm for the clinical human genetic work-up reflecting the German health care system options and gives information with regard to the obligatory genetic counselling after a clinical genetic assessment.

Publisher

Walter de Gruyter GmbH

Subject

Genetics (clinical),Genetics

Link

https://www.degruyter.com/document/doi/10.1515/medgen-2020-2001/pdf

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