Preparation and characterization of magnetic microgels with linear thermosensitivity over a wide temperature range-Reference-Cited by-同舟云学术

Preparation and characterization of magnetic microgels with linear thermosensitivity over a wide temperature range

Published:2023-01-01 Issue:1 Volume:23 Page:
ISSN:1618-7229
Container-title:e-Polymers
language:en
Short-container-title:

Author:

Yang Yongqi¹,Ren Zekai²,Li Xiawei³,Yan Youjun¹,Liu Jun¹,Lian Meng¹,Liu Guangyao⁴,Luo Xin⁵

Affiliation:

1. Shandong Engineering Laboratory for Clean Utilization of Chemical Resources, Weifang University of Science and Technology , Weifang , 262700 , China

2. College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University , Qingdao 266071 , China

3. Inner Mongolia Institute of Quality and Standardization, Inner Mongolia Administration for Market Regulation , Hohhot 010000 , China

4. Institute of Optical Functional Materials for Biomedical Imaging, School of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Sciences , Tai’an , Shandong 271016 , P. R. China

5. Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University , Dezhou 253023 , China

Abstract

Abstract Hybrid nanogels that are both thermosensitive and superparamagnetic, and have good biocompatibility are expected to have applications in the biomedical field. In this article, a linearly thermosensitive magnetic microgel was prepared by a radical copolymerization reaction in aqueous dispersion. In this reaction, poly(ethylene glycol) diacrylate was used as a crosslinker, polyvinylpyrrolidone was used as a stabilizer, and 2-methoxyethyl acrylate, poly(ethylene glycol)methyl ether acrylate, and 2-(methacryloyloxy)ethyl acetoacetate were used as copolymer monomers. The thermosensitive magnetic microgel displays a linear volume phase transition in water upon heating over a wide range of temperatures. Transmission electron microscopy, scanning electron microscopy, and dynamic light scattering were used to characterize the morphology and dimensions of the thermosensitive magnetic microgel. This material is expected to be used in magnetically targeted drug delivery systems that require linear drug release.

Publisher

Walter de Gruyter GmbH

Subject

Polymers and Plastics,Physical and Theoretical Chemistry,General Chemical Engineering

Link

https://www.degruyter.com/document/doi/10.1515/epoly-2023-0161/pdf

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