The involvement of the central nervous system in patients with COVID-19

Author:

Saleki Kiarash1,Banazadeh Mohammad1,Saghazadeh Amene12,Rezaei Nima234

Affiliation:

1. Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, 14194, Iran

2. Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Dr. Qarib St, Keshavarz Blvd, Tehran, 14194, Iran

3. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, 14194, Iran

4. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, 14194, Iran

Abstract

AbstractCoronaviruses disease (COVID-19) has caused major outbreaks. A novel variant, SARS-CoV-2, is responsible for COVID-19 pandemic. Clinical presentations and pathological mechanisms of COVID-19 are broad. The respiratory aspect of the disease has been extensively researched. Emerging studies point out the possibility of the central nervous system (CNS) involvement by COVID-19. Here, we discuss the current evidence for CNS involvement in COVID-19 and highlight that the high pathogenicity of SARS-CoV-2 might be due to its neuroinvasive potential.

Publisher

Walter de Gruyter GmbH

Subject

General Neuroscience

Reference26 articles.

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