Tryptophan hydroxylase 2 in seasonal affective disorder: underestimated perspectives?-Reference-Cited by-同舟云学术

Tryptophan hydroxylase 2 in seasonal affective disorder: underestimated perspectives?

Published:2015-01-01 Issue:6 Volume:26 Page:
ISSN:2191-0200
Container-title:Reviews in the Neurosciences
language:
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Author:

Kulikov Alexander V.,Popova Nina K.

Abstract

AbstractSeasonal affective disorder (SAD) is characterized by recurrent depression occurring generally in fall/winter. Numerous pieces of evidence indicate the association of SAD with decreased brain neurotransmitter serotonin (5-HT) system functioning. Tryptophan hydroxylase 2 (TPH2) is the key and rate-limiting enzyme in 5-HT synthesis in the brain. This paper concentrates on the relationship between TPH2 activity and mood disturbances, the association between human

Publisher

Walter de Gruyter GmbH

Subject

General Neuroscience

Link

https://www.degruyter.com/document/doi/10.1515/revneuro-2015-0013/pdf

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