High Sensitivity in CID Mass Spectrometry, Structure Analysis of Pyrolysis Fragments

Abstract

Abstract Collision Induced Dissociation (C ID),C ollisional Activation (CA), Pyrolysis, Mycobacterium, Mass Spectrometry An apparatus is described for Collision Induced Dissociation Mass Spectrometry, where es­ sential increase in sensitivity in the detection of the fragment spectrum is obtained by simultaneous detection. Decrease in resolution due to kinetic energy release on dissociation is prevented by post-acceleration of the fragment ions. The instrument was used to investigate the structure of the mass m/z= 59 com pound in the pyrolysis products of Mycobacterium cells. This mass is a key mass in the pyrolysis mass spectrometric identification of dangerous mycobacterial strains.