Author:
Diringers H.,Kulas H.-P.,Schneider L. G.,Schlumberger H. D.
Abstract
The lipid composition of the Flury HEP strain of rabies virus grown in BHK 21/C 13 cells was determined. The dried purified virus preparation contains 5.5 % neutral and 19.5 % polar lipids. Cholesterol was found to be the major neutral lipid. Phopholipids constitute 11.2 %; and glycolipids represent 4.6 % of the virus mass. The residual 3.7 % of extracted polar lipid material could not be accounted for by any known lipids. Phosphatidylethanolamine, phosphatidylcholine and sphingomyelin are the main constituents of the viral phospholipids. Hema- toside is the only ganglioside and the main glycolipid present in the virus. The glycolipids of the host cell and the virus are identical. The molar ratio of sphingolipids to glycerophospho-lipids is 0.8.
Subject
General Biochemistry, Genetics and Molecular Biology
Cited by
9 articles.
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