Affiliation:
1. Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Abstract
Abstract
Background
Malignant (high-grade) gliomas are rapidly progressive brain tumours with very high morbidity and mortality. Until recently, treatment options for patients with malignant gliomas were limited and mainly the same for all subtypes of malignant gliomas. The treatment included surgery and radiotherapy. Chemotherapy used as an adjuvant treatment or at recurrence had a marginal role.
Conclusions
Nowadays, the treatment of malignant gliomas requires a multidisciplinary approach. The treatment includes surgery, radiotherapy and chemotherapy. The chosen approach is more complex and individually adjusted. By that, the effect on the survival and quality of life is notable higher.
Subject
Radiology, Nuclear Medicine and imaging,Oncology
Reference82 articles.
1. WHO Classification of tumours of the central nervous system. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, editors. Lyon: IARC Press; 2007.
2. CBTRUS, Central Brain Tumor Registry of the United States. 2007–2008. Primary brain tumors in the United States. Statistical report. 2000– 2004 years of data collected. Available from: http://www.cbtrus.org/ reports/2007-2008/2007report.pdf. Accessed on 10 November 2013.
3. Kase M, Minajeva A, Niinepuu K, Kase S, Vardja M, Asser T, et al. Impact of CD133 positive stem cell proportion on survival in patients with glioblastoma multiforme. Radiol Oncol 2013; 47: 405-10.
4. Fisher JL, Schwartzbaum JA, Wrensch M, Wiemels JL. Epidemiology of brain tumors. Neurol Clin 2007; 25: 867-90.
5. Smrdel U, Kovac V, Popovic M, Zwitter M. Glioblastoma patients in Slovenia from 1997 to 2008. Radiol Oncol 2014; 48: 72-9.
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