Well-Differentiated Liposarcoma of The Larynx: A Case Report and Review of Literature

Author:

Mateva Svetlana A.1,Nikolova Margarita R.2,Valkov Alexandar V.3,Nikolova Margarita R.3

Affiliation:

1. Department of Patholoanatomy, Faculty of Medicine, Medical University - Pleven, Bulgaria

2. Department of Patholoanatomy, Medical University - Pleven l, St. Kliment Ohridski Str. Pleven, 5800, Bulgaria

3. Department of Otolaryngology, Faculty of Medicine, Medical University - Pleven, Bulgaria

Abstract

Summary Liposarcoma is one of the most common soft tissue sarcomas in adults with a relative incidence amongst other sarcomas ranging from 9.8% to 16%. It usually locates in the limbs and retroperitoneum. Primary liposarcomas of the larynx and hypopharynx are rare, comprising less than 20% of all head and neck liposarcomas. According to World Health Organization, these tumors are divided into four histologic types, and well-differentiated liposarcoma is the most common one. It is a tumor of low-grade malignancy that may recur locally, but does not metastasize. We present a case of laryngopharyngeal well- differentiated liposarcoma in an old patient with two previous removals. We also discuss recently published cases with this unusual location of liposarcoma.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Reference37 articles.

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2. 2. Fletcher CDM, Unni K.K, Mertens F, editors. World Health Organization classification of tumours. Pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002.

3. 3. Barnes L, Eveson LW, Reichard P, Sidransky D, editors. World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005.

4. 4. Sanz Gonzalo JJ, P. Martinez Molina P, Ribalta Farres MT, Sabater Matadelabarata F. Liposarcoma of the hypopharynx. Acta Otorrinolaryngol Esp. 2002;53( 1): 60-3.

5. 5. Almela Cortis R, Moreno Carazo A, Martin Rodriguez L. Laryngeal and hypopharyngeal liposarcoma. Report of a case and literature review. An Otorrinolaringol Ibero Am. 2002;29(5):431-8.

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