A short review on cancer therapeutics

Abstract

Abstract Cancer as a disease has been a remarkable scourge and over the past years, advances have been made in understanding the molecular basis of carcinogenesis and combating this disease. The common traits exhibited by cancer have been individually studied to figure out its mode of action and its mechanism of survival even in the most austere conditions. The various hallmarks noted so far have been effectively studied and different therapies revolving around each hallmark are still being studied in order to find the most appropriate treatment for the different types of cancer in existence. Emerging therapies have been able to elucidate the mechanism of receptor blockage which facilitate the ability of cancer to proliferate as well as evade tumor suppressors, prevent cell death, support replicative immortality, escape immune destruction, stimulate angiogenesis, reduce cellular energetics as well as metabolism and prevent the destruction of the immune system. This life-threatening disease should be tackled aggressively with a combined therapy that involves two or more hallmarks of cancer and adverse effects of each therapy should also be considered.