Celiac Disease and Cystic Fibrosis: Challenges to Differential Diagnosis

Author:

Ramos Alessandra Teixeira Pessoa,Figueirêdo Manuella Machado,Aguiar Ana Paula de B.,Almeida Carolina de Godoy,Mendes Patrícia S. A.,Souza Edna Lucia

Abstract

Abstract Cystic fibrosis and celiac disease were considered a single clinical entity for many years. Differentiation between the diseases occurred some time in the 1930s of the 20th Century. Both diseases may present the intestinal malabsorption syndrome and similar clinical manifestations that contribute to difficulties with clinical distinction. We describe a report of two patients with initial diagnosis of cystic fibrosis, who were subsequently diagnosed with celiac disease. These case reports emphasize the possibility of false positivity being shown in the sweat test in CD, which may result in delayed diagnosis and inadequate management of this disease.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

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1. Brazilian Guidelines for Nutrition in Cystic Fibrosis;Einstein (São Paulo);2022

2. Elevated sweat chloride test: is it always cystic fibrosis?;Italian Journal of Pediatrics;2021-05-14

3. The first report on the association of celiac disease and cystic fibrosis in a tertiary care center in Saudi Arabia;International Journal of Pediatrics and Adolescent Medicine;2021-05

4. Does cystic fibrosis make susceptible to celiac disease?;European Journal of Pediatrics;2021-03-25

5. Celiac disease: Understandings in diagnostic, nutritional, and medicinal aspects;International Journal of Immunopathology and Pharmacology;2021-01

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