1. University of Dundee, School of Nursing and Health Sciences , Dundee , UK
2. University of Oxford, Nuffield Department of Primary Care Health Sciences , Oxford , UK
3. University of Manchester, Centre for Musculoskeletal Research, School of Biological Sciences, Faculty of Biology, Medicine and Health , Manchester , UK
4. NIHR Manchester Biomedical Research Centre , Manchester University NHS Foundation Trust , Manchester , UK
5. Manchester Academic Health Science Centre , Manchester , UK