Enhancing retention in care in HIV-infected adolescents during COVID-19 in Mozambique: results from the DREAM program

Author:

Ciccacci Fausto1ORCID,Ismael Flavio2,Chume Veronica2,Ruth Lina2,Mbula Pedro3,Orlando Stefano4,Majid Noorjehan Abdul2,Marazzi Maria Cristina5

Affiliation:

1. UniCamillus – Saint Camillus International University of Health and Medical Sciences , Rome , Italy

2. DREAM program , Community of Sant’Egidio , Maputo , Mozambique

3. DREAM program , Community of Sant’Egidio , Beira , Mozambique

4. Department of Biomedicine and Prevention , University of Rome Torvergata , Rome , Italy

5. LUMSA University , Rome , Italy

Abstract

Abstract Introduction Around 1,7 million adolescents aged 10–19 years worldwide are infected with HIV, 84% of them living in Sub-Saharan Africa. Mozambique is one of the countries with the highest prevalence of HIV in the world. According to UNAIDS, HIV services for adolescents should be tailored and specifically designed for them. Methods We aimed to evaluate a package of activities to enhance the retention of HIV-infected adolescent in Mozambique. We retrospectively reviewed routine data from 7 health centers involved in 26 months, from March 2020 to May 2022. A package of tailored interventions was implemented in all the sites. We reviewed activity data from the included centers. Results The median number of patients per center was 343 (IQR: 289–466) at the beginning of the period and 395 (IQR: 322–453) at the end. The median overall retention in care and rate of lost to follow-up at the beginning and the end of the period were respectively: 94.2% (IQR 91.9–97.3%) to 99.0% (IQR 96.8–99.5%), 1.5% (IQR 1–3.2%) to 0% (IQR 0.0–0.3%). The total number of deaths increased reaching a plateau after September 2021. All the indicators improved after the beginning of the intervention, also during COVID-19 pandemic. Conclusions Our data support the idea that enhancing retention in care for HIV positive adolescents need tailored interventions, based on deep rooting in the specific social context. Tailored intervention can resist external shock such as COVID-19.

Funder

Agenzia Italiana per la Cooperazione allo Sviluppo

Publisher

Walter de Gruyter GmbH

Subject

Public Health, Environmental and Occupational Health,Pediatrics, Perinatology and Child Health

Reference24 articles.

1. UNAIDS. AIDS info. Available from: https://aidsinfo.unaids.org (Accessed 4 Nov 2022).

2. Enane, LA, Vreeman, RC, Foster, C. Retention and adherence: global challenges for the long-term care of adolescents and young adults living with HIV. Curr Opin HIV AIDS 2018;13:212–9. https://doi.org/10.1097/coh.0000000000000459.

3. Auld, AF, Agolory, SG, Shiraishi, RW, Wabwire-Mangen, F, Kwesigabo, G, Mulenga, M, et al.. Antiretroviral therapy enrollment characteristics and outcomes among HIV-infected adolescents and young adults compared with older adults--seven African countries, 2004-2013. MMWR Morb Mortal Wkly Rep 2014;63:1097–103.

4. Ciccacci, F, Orlando, S, Sagno, JB, Kamponda, M, Gondwe, J, Lunghi, R, et al.. Evaluation of nutritional conditions, haemoglobin levels, retention in care and viral suppression in a cohort of HIV-infected Malawian adolescents undergoing a one-year tailored intervention within the diseases relief through excellence and advanced means. South Afr J Child Health 2020;14:228. https://doi.org/10.7196/sajch.2020.v14i4.01751.

5. UNAIDS. Country factsheets – Mozambique 2021; 2021. Available from: https://www.unaids.org/en/regionscountries/countries/mozambique.

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