Zinc-Selenium reagents in organic synthesis

Abstract

Abstract Organoselenolates, due to the high polarizability of the chalcogen atoms, are generally weak bases and soft nucleophiles used to introduce in stereoselective and mild way a selenium functionality through substitution or addition reactions. Among several methods reported for their preparation, recently the reduction of Se-Se or Se-Halogen bond mediated by elemental zinc becomes particularly attractive for the simplicity and the efficiency of the protocols. An overview on the most recent developments in the field is here reported.