Affiliation:
1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, A. R. Egypt
2. Institut für Organische Chemie der Universität Graz, Heinrichstraße 28, A-8010 Graz (Austria)
Abstract
The synthesis of 2,5-disubstituted 5,6-dihydro-1 H-pyrido[1,2-a]quinazoline-1,6-diones (3) by reacting monosubstituted bis 2,4,6-trichlorophenyl malonates (1) with 3-aryl-3,4- dihydro-2-methyl-4-quinazolinones (2) is described. Allylation of the pyridoquinazoline 3c with allylbromide afforded the corresponding 3-allyloxy derivative 4. Certain generalizations of the cleavage processes of this series in the MS are reported.
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Synthesis and structure of pyrido[1,2-a]quinazoline condensed derivatives;Synthetic Communications;2020-05-18
2. References;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02
3. Bis(2,4,6-trichlorophenyl) Malonate;Encyclopedia of Reagents for Organic Synthesis;2001-04-15
4. Methylpyridines and Other Methylazines as Precursors to Bicycles and Polycycles;Advances in Heterocyclic Chemistry;1997
5. Volume 8 References;Comprehensive Heterocyclic Chemistry II;1996