Towards correlative archaeology of the human mind
Author:
Piszczek Lukasz1, Kaczanowska Joanna2, Haubensak Wulf13ORCID
Affiliation:
1. Department of Neuronal Cell Biology , Center for Brain Research, Medical University of Vienna , A-Vienna , Austria 2. a:head bio , Dr.-Bohr-Gasse 7, VBC6, A-1030 Vienna , Austria 3. Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC) , Campus-Vienna-Biocenter 1, A-1030 Vienna , Austria
Abstract
Abstract
Retracing human cognitive origins started out at the systems level with the top-down interpretation of archaeological records spanning from man-made artifacts to endocasts of ancient skulls. With emerging evolutionary genetics and organoid technologies, it is now possible to deconstruct evolutionary processes on a molecular/cellular level from the bottom-up by functionally testing archaic alleles in experimental models. The current challenge is to complement these approaches with novel strategies that allow a holistic reconstruction of evolutionary patterns across human cognitive domains. We argue that computational neuroarcheology can provide such a critical mesoscale framework at the brain network-level, linking molecular/cellular (bottom-up) to systems (top-down) level data for the correlative archeology of the human mind.
Funder
FP7 Ideas: European Research Council Austrian Science Fund
Publisher
Walter de Gruyter GmbH
Subject
Clinical Biochemistry,Molecular Biology,Biochemistry
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