Predictors of Postoperative Outcome in Patients with Lower Limb Surgical Revascularization

Author:

Cosmin Caraşca1,Emilian Caraşca2,Ioan Ţilea3,Septimiu Voidazan4,Alexandru Incze2

Affiliation:

1. Department of Forensic Medicine, University of Medicine and Pharmacy of Tîrgu-Mureş, Romania

2. Department of Internal Medicine, Tîrgu Mureș County Hospital, University of Medicine and Pharmacy of Tîrgu-Mureş, Romania

3. Cardiovascular Rehabilitation Clinic, Department M3 Family Medicine, Institute of Cardiovascular Diseases and Transplantation Tîrgu-Mures, Romania

4. Department of Epidemiology, University of Medicine and Pharmacy of Tîrgu-Mureş, Romania

Abstract

Abstract Objective: In patients with critical limb ischemia who undergone revascularization procedures, the assessment of risk factors that may affect the postoperative outcome is of great importance. The main objective in this study is to assess the utility of two specific risk scores, the Finnvasc score and the modified Prevent III score. Methods: We evaluated the applicability of these two risk scores in 150 patients who undergone an unilateral infrainguinal surgical revascularization procedure. The receiver operating characteristic curve analysis was used to estimate the predictive value of the scoring methods. A comparison between the risk scores, determine the areas under the curve. Medium-term prediction ability was analyzed for both scoring methods. Results: The area under the curve of Finnvasc score for predicting amputation was 0.739 (95%CI:0.661-0.807) and of the modified PIII score 0.713 (95%CI:0.633-0.784); for restenosis we obtained 0.528 (95%CI:0.444-0.611), respectively 0.529 (95%CI:0.445-0.612) and for thrombosis 0.628 (95%CI:0.544-0.706) and 0.556 (95%CI:0.472-0.638), demonstrating that the Finnvasc score performs better in overall prediction. Heart failure is a strong independent predictor of amputation (p=0.0001, OR=26.90; 95%CI:5.81-124.2), restenosis (p=0.0003, OR=4.80; 95%CI:1.96-11.8) and mortality (p=0.01, OR=7.16; 95%CI:1.33-38.52). Conclusions: The accuracy of the two risk scoring methods in predicting the medium-term outcome of patients undergoing surgical infrainguinal revascularization is acceptable. The Finnvasc score is easier to be applied to the characteristics of our patients.

Publisher

Walter de Gruyter GmbH

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Dentistry

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