Affiliation:
1. Ontario HIV Treatment Network (OHTN), Toronto, Canada
2. Centre for Addiction and Mental Health (CAMH), Toronto, Canada
3. Department of Psychiatry, University of Toronto; Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada
Abstract
AbstractBehavioral interventions can prevent the transmission of HIV and sexually transmitted infections. This systematic review and meta-analysis assesses the effectiveness and quality of available evidence of HIV prevention interventions for people living with HIV in high-income settings. Searches were conducted in MEDLINE, EMBASE, PsycINFO, and CDC Compendium of Effective Interventions. Interventions published between January, 1998 and September, 2015 were included. Quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Forty-six articles and 63 datasets involving 14,096 individuals met inclusion criteria. Included articles were grouped by intervention type, comparison group and outcome. Few of these had high or moderate quality of evidence and statistically significant effects. One intervention type, group-level health education interventions, were effective in reducing HIV/STI incidence when compared to attention controls. A second intervention type, comprehensive risk counseling and services, was effective in reducing sexual risk behaviors when compared to both active and attention controls. All other intervention types showed no statistically significant effect or had low or very low quality of evidence. Given that the majority of interventions produced low or very low quality of evidence, researchers should commit to rigorous evaluation and high quality reporting of HIV intervention studies.
Reference3 articles.
1. Sexual risk reduction for HIV - infected persons : A meta - analytic review of positive prevention randomized clinical trials PLoS ONE GRADE handbook for grading quality of evidence and strength of recommen - dations Available from www;Schunemann;Updated October,2014
2. html Accessed Tungol Ashmon A systematic review of interventions for reducing HIV risk behaviors among people living with HIV in the United States;Crepaz;AIDS,2014
3. Psychology Press et al GRADE guidelines Preparing Summary of Findings tables - binary outcomes Furukawa TA GRADE guidelines Preparing Summary of Findings tables and evidence profiles continuous outcomes;Guyatt;J Clin Epidemiol J Clin Epidemiol,1988
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献