Synthesis of nicotinamide-imprinted polymers and their binding performances in organic and aqueous media

Author:

Mookda Pattarawarapan1,Singha Komkham2,Weeranuch Kareuhanon1,Chatchai Tayapiwatana3

Affiliation:

1. 1Department of Chemistry, Faculty of Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand; fax: 66 53 892277

2. 2Department of Chemistry, Faculty of Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand; fax: 66 53 892277; 2 Division of Clinical Immunology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand; fax: 66 53 9460

3. 3Division of Clinical Immunology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand; fax: 66 53 9460

Abstract

AbstractTo obtain molecularly imprinted polymers capable of selective rebinding with nicotinamide (NAM), NAM imprinted polymers were synthesized via bulk polymerization using various functional monomers and cross-linkers. The NAM recognition properties of these polymers were investigated in organic and aqueous solvents by equilibrium rebinding experiments. The results show that the imprinted polymer prepared using 1:4:4 molar ratio of NAM/MAA/TRIM in dichloromethane exhibited the greatest NAM binding capacity and selectivity. This polymer is potentially valuable for the analysis of NAM in complex matrices where selective isolation and identification are needed.

Publisher

Walter de Gruyter GmbH

Subject

Polymers and Plastics,Physical and Theoretical Chemistry,General Chemical Engineering

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