Congenital adrenal hyperplasia. Role of dentist in early diagnosis-Reference-Cited by-同舟云学术

Congenital adrenal hyperplasia. Role of dentist in early diagnosis

Published:2022-01-01 Issue:1 Volume:17 Page:1699-1704
ISSN:2391-5463
Container-title:Open Medicine
language:en
Short-container-title:

Author:

Di Cosola Michele¹,Spirito Francesca¹²,Zhurakivska Khrystyna¹,Nocini Riccardo³,Lovero Roberto⁴,Sembronio Salvatore⁵,Santacroce Luigi⁶,Brauner Edoardo⁷,Storto Giovanni⁸,Lo Muzio Lorenzo¹,Cazzolla Angela Pia¹

Affiliation:

1. Department of Clinical and Experimental Medicine, University of Foggia , Foggia , Italy

2. Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana,” University of Salerno , Via Allende, 84081 , Baronissi (SA) , Italy

3. ENT Department, University of Verona , 37100 , Verona , Italy

4. Clinical Pathology Unit, AOU Policlinico Consorziale di Bari - Ospedale Giovanni XXIII , 70124 , Bari , Italy

5. Department of Maxillofacial Surgery, University of Udine, Academic Hospital “Santa Maria della Misericordia,” , 33100 , Udine , Italy

6. Department of Interdisciplinary Medicine, Microbiology and Virology Laboratory, University Hospital of Bari, Università degli Studi di Bari , 70124 , Bari , Italy

7. Department of Dental and Maxillary Facial Sciences, “Sapienza” University of Rome , 00185 , Rome , Italy

8. Nuclear Medicine Unit, IRCCS Regional Cancer Hospital CROB, Referral Cancer Center of Basilicata , 85028 , Potenza , Italy

Abstract

Abstract Congenital adrenal hyperplasia (CAH) is a genetic disorder characterized by an impairment of steroid synthesis due to an altered production of 21-hydroxylase enzyme. Corticoid hormones are involved in the development and functioning of many organs. The aim of the present study was to review the international literature to collect data regarding oral manifestations of CAH. A review of the literature describing oral features of patients affected by CAH was performed using electronic databases (PubMed and Scopus). The data about number of patients, form of CAH, and oral findings were extracted and analyzed. Seven studies were included in the final analysis. The principal findings reported regarded an advanced dental development observed in patients with CAH. One paper reported amelogenesis imperfecta and periodontal issues. The dentist could be the first specialist involved in the CAH syndrome diagnosis, identifying the characteristic features described above, especially for the classical simple virilizing and non-classical form.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

https://www.degruyter.com/document/doi/10.1515/med-2022-0524/pdf

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