Ring transformation and antimicrobial activity of indolyl-substituted 2(3H)-furanones-Reference-Cited by-同舟云学术

Ring transformation and antimicrobial activity of indolyl-substituted 2(3H)-furanones

Published:2015-06-01 Issue:3 Volume:21 Page:179-185
ISSN:2191-0197
Container-title:Heterocyclic Communications
language:
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Author:

Abou-Elmagd Wael S.I.¹,EL-Ziaty Ahmed K.¹,Abdalha Abdelaal A.

Affiliation:

1. 1Faculty of Science, Chemistry Department, Ain Shams University, Abassia, Cairo 11566, Egypt

Abstract

AbstractA variety of heterocycles of synthetic and biological importance were prepared from 3-(indol-3-yl-methylene)-5-phenyl-2(3H)-furanone (1) and its hydrazide 2. Compounds 1 and 2 were used for the construction of pyridazin-3(4H)-ones 4 and 6; 1,3,4-oxadiazoles 7, 8, and 10; and 1,2,4-triazoles 12, 14, and 15, all bearing a 3-indolyl moiety. The antimicrobial activities of the synthesized compounds were examined against six types of bacteria and two types of fungi.

Publisher

Walter de Gruyter GmbH

Subject

Organic Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/hc-2015-0008/pdf

Reference64 articles.

1. Conversion of α aracyl β thienyl acroyl semicarbazides into triazole derivatives;Yassin;Rev Roum Chim,1996

2. Acetyl methyl nitro phenyl pyridazinone versatile precursor to hetero - condensed pyridazinones Synthesis;Piaz,1994

3. Reactions of furanones;Hashem;Adv Heterocycl Chem,1999

4. Moo Antimicrobial activity of the ethanol extract of the aerial parts of Sida acuta;Irobi;Young Int J,1996

5. Acetyl methyl nitro phenyl pyridazinone versatile precursor to hetero - condensed pyridazinones Synthesis;Piaz,1994

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