An efficient, one-pot three-component synthesis of 4H-thiazolo[3,2-a][1,3,5]triazin-6-one derivatives-Reference-Cited by-同舟云学术

An efficient, one-pot three-component synthesis of 4H-thiazolo[3,2-a][1,3,5]triazin-6-one derivatives

Published:2016-02-01 Issue:1 Volume:22 Page:43-47
ISSN:2191-0197
Container-title:Heterocyclic Communications
language:
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Author:

Ubeid Mustafa T.¹,Thabet Hamdy K.¹²,El-Feky Said A.³

Affiliation:

1. 1Faculty of Arts and Science, Department of Chemistry, Northern Border University, Rafha, 91911, P.O. 840, Saudi Arabia

2. 2Faculty of Science, Department of Chemistry, Al-Azhar University, 11284, Nasr City, Cairo, Egypt

3. 3Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Northern Border University, Rafha, 91911, P.O. 840, Saudi Arabia

Abstract

AbstractA simple and efficient protocol was established to synthesize thiazolo[3,2-a][1,3,5]triazin-6-ones via three-component one-pot condensation reaction of readily available thioglycolic acid or ethyl thioglycolate, aldehydes or ketones and dicyandiamide in the presence of ammonium acetate. All of the newly synthesized compounds were characterized by spectroscopic analyses.

Publisher

Walter de Gruyter GmbH

Subject

Organic Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/hc-2015-0135/pdf

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