Juglomycins G-J: Isolation from Streptomycetes and Structure Elucidation-Reference-Cited by-同舟云学术

Juglomycins G-J: Isolation from Streptomycetes and Structure Elucidation

Published:2005-02-01 Issue:2 Volume:60 Page:183-188
ISSN:1865-7117
Container-title:Zeitschrift für Naturforschung B
language:
Short-container-title:

Author:

Maskey R. P.¹,Lessmann H.¹,Fotso S.¹,Grün-Wollny I.²,Lackner H.¹,Laatsch H.¹

Affiliation:

1. 1Department of Organic and Biomolecular Chemistry, University of Göttingen, Tammanstraße 2, D-37077 Göttingen, Germany

2. 2Department of Organic and Biomolecular Chemistry, University of Göttingen, Versaillerstraße. 1, D-35394 Giessen

Abstract

From the Streptomyces spp. 815 and GW4184, four new 4-juglon-2-ylbutyric acid derivatives, the juglomycins G - J (3a, 4a, 4c, 5c), have been isolated and characterised. The structures were derived from the 1D and 2D NMR data and mass spectra and confirmed by comparison with structurally related compounds. The absolute configuration was deduced from the CD spectra. The new natural products exhibited weak antibacterial activity similar to juglomycin A (5a).

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/znb-2005-0210/pdf

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